The Georgia Poison Center is reporting a sharp rise in emergency calls related to GLP-1 drugs, which were originally developed to treat diabetes but are increasingly used for weight loss. Experts warn that improper use and dosage mistakes are driving the surge in overdoses.
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What Happened
GLP-1 drugs, also known as glucagon-like peptide-1 receptor agonists, have seen growing popularity as a weight loss solution. Initially approved for diabetes management, these medications now attract users seeking weight reduction.
- Calls Received:
- 2023: 129 calls
- 2024: 246 calls
- 2025 (so far): 254 calls
The majority of these calls involve first-time users who accidentally take incorrect doses, often due to insufficient guidance, confusion, or unregulated online sources.
Who Uses GLP-1 Drugs?
GLP-1 drugs help regulate blood sugar and appetite. The FDA has approved synthetic versions for diabetes, and some are also approved for weight loss in obese patients. As demand for weight loss solutions grows, more individuals are using these drugs without adequate supervision, increasing the risk of overdose.
Why Are Overdose Cases Rising?
The surge in overdose calls is largely linked to confusion about proper administration.
- About 75% of overdose cases involve first-time users who are unsure how to inject the drug correctly.
- Some patients purchase medications from unlicensed online pharmacies, increasing the risk of misuse.
Side Effects and Risks
Common side effects include:
- Nausea and vomiting
- Abdominal pain
- Changes in heart rate
- Blood sugar fluctuations
While mild in most cases, overdoses can require emergency room treatment, as reported in over 40% of calls to the Georgia Poison Center.
Lopez, Executive Director of the Poison Center, warns:
“With the increasing popularity of GLP-1 drugs, the situation may worsen before it improves.”
Public Reactions and Social Media Concerns
Many users turn to online forums and social media for advice on GLP-1 usage. Experts caution against relying solely on these sources, as misinformation about dosing can lead to dangerous mistakes. Public awareness about the risks of overdose is growing alongside the drugs’ popularity.
What You Should Do
Experts recommend:
- Confirm proper dosage with a licensed pharmacy
- Avoid taking multiple doses at once
- Purchase medications only from licensed pharmacies
If you suspect an overdose or have questions about GLP-1 use, contact the Poison Help Line:
- 1-800–222–1222
- Alternatively, save the direct line: 301-597-7137
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